SCHEMBL1058149

SCHEMBL1058149

[CH]N(CCCC)CCCC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
LMNA P02545 1/20 0.43
DNM1 Q05193 3/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA9 Q16790 3/20 0.38
ALDH1A1 P00352 2/20 0.38
ALDH2 P05091 1/20 0.38
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
CA2 P00918 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5452466 0.75
Ethyne SCHEMBL28308838 0.74 CA12 (0.42) TSHRLMNADNM1THRBCA12
SCHEMBL20212033 0.72 TSHR (0.46) TSHRLMNADNM1THRBCA12
SCHEMBL27566038 0.72 TSHR (0.46) TSHRLMNADNM1THRBCA12
SCHEMBL896 0.72 TSHR (0.46) TSHRLMNADNM1THRBCA12
SCHEMBL3904839 0.72 TSHR (0.46) TSHRLMNADNM1THRBCA12
SCHEMBL15486339 0.72 DNM1 (0.67) TSHRLMNADNM1THRBCA12
SCHEMBL19850597 0.72
Cyanide SCHEMBL1998468 0.72 CA12 (0.40) TSHRLMNADNM1THRBCA12
SCHEMBL464950 0.69 TSHR (0.36) TSHRLMNADNM1THRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111712529-A Method and composition for preparing thermosetting poly (arylene ether) copolymer 沙特基础工业全球技术有限公司 2020-09-25 CN claimed
EP-2921499-B1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-22 EP claimed
EP-3571241-A1 PROCESS FOR THE MANUFACTURE OF THERMOSETTING POLY(ARYLENE ETHER) COPOLYMER AND COMPOSITIONS SABIC Global Technologies B.V. (NL) 2019-11-27 EP claimed
CN-110317197-A A kind of aminomethyl substituted silibinin derivative and its preparation method and application 天士力医药集团股份有限公司 2019-10-11 CN claimed
WO-2019116309-A1 PROCESS FOR THE MANUFACTURE OF THERMOSETTING POLY(ARYLENE ETHER) COPOLYMER AND COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-20 WO claimed
EP-1112281-B1 PTERIDINE NUCLEOTIDE ANALOGS US GOV HEALTH & HUMAN SERV (US) 2005-11-23 EP claimed
EP-1112281-A1 PTERIDINE NUCLEOTIDE ANALOGS THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services (US) 2001-07-04 EP claimed
WO-2000014101-A1 PTERIDINE NUCLEOTIDE ANALOGS THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-03-16 WO claimed
EP-0759927-B1 PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES US GOV HEALTH & HUMAN SERV (US) 1998-06-24 EP claimed
EP-0759927-A1 PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1997-03-05 EP claimed
US-5525711-A MONOMERS FOR DNA AMPLIFICATION PROCEDURES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-06-11 US claimed
WO-1995031469-A1 PTERIDINE NUCLEOTIDE ANALOGS AS FLUORESCENT DNA PROBES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-11-23 WO claimed
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 EP claimed
WO-1993025566-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA JYOTI (SE) 1993-12-23 WO claimed
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT INTEGRATED DNA TECHNOLOGIES, INC. 2023-04-20 US disclosed
CN-111712529-B Method and composition for preparing thermosetting poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2023-02-28 CN disclosed
CN-111712529-B Method and composition for preparing thermosetting poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2023-02-28 CN disclosed
EP-0196101-B1 PURIFICATION OF SYNTHETIC OLIGOMERS CHIRON CORP (US) 1991-05-02 EP disclosed
EP-0398391-A1 0,0'-Dicyanoethyl-phosphoramidites, a process for their preparation and their use in phosphorylation reactions CHIRON CORPORATION (US) 1990-11-22 EP disclosed
EP-0196101-A2 Purification of synthetic oligomers CHIRON CORPORATION (US) 1986-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230119227-A1 OLIGONUCLEOTIDE SYNTHESIS ON SOLID SUPPORT RNGTT, SSU72, NSUN2 TSHR 2212/4885LMNA 1861/4885DNM1 2093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.