Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583786 | 0.96 | TBXA2R (0.51) | TBXA2RTBXAS1HSD11B1PTGDR2EGFR | |
| SCHEMBL10583029 | 0.95 | TBXA2R (0.50) | TBXA2RTBXAS1HSD11B1PTGDR2EGFR | |
| SCHEMBL10580163 | 0.89 | TBXAS1 (0.54) | TBXAS1HSD11B1PTGDR2EGFRERBB2 | |
| SCHEMBL10580993 | 0.86 | POLB (0.50) | TBXAS1HSD11B1EGFRERBB2HTT | |
| SCHEMBL3250400 | 0.86 | TBXA2R (0.62) | TBXA2RHSD11B1EGFRERBB2GAA | |
| SCHEMBL10580558 | 0.83 | ALDH1A1 (0.49) | TBXAS1HSD11B1EGFRERBB2HTT | |
| SCHEMBL10584188 | 0.82 | TBXA2R (0.60) | TBXA2RHSD11B1EGFRERBB2GAA | |
| SCHEMBL19281469 | 0.82 | MGLL (0.55) | TBXA2RGAAALDH1A1TP53CYP19A1 | |
| SCHEMBL9813812 | 0.81 | PPARA (0.57) | PTGDR2 | |
| SCHEMBL9320853 | 0.81 | GAA (0.62) | HSD11B1GAAHTTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |