Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GPX4 | P36969 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446163 | 0.86 | MAPT (0.53) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL1250870 | 0.86 | MAPT (0.53) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL10582546 | 0.84 | CES2 (0.51) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL1252550 | 0.82 | MAPT (0.50) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL8391459 | 0.82 | ALDH1A1 (0.48) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL11146469 | 0.82 | ALDH1A1 (0.50) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL10583176 | 0.81 | ALDH1A1 (0.45) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL9651135 | 0.81 | MAPT (0.46) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL28820283 | 0.81 | MAPT (0.60) | MAPTLMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL397442 | 0.80 | GFER (0.54) | MAPTLMNAUSP2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297710-A1 | Disperse dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-04 | — | — | EP | disclosed |