Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GPX4 | P36969 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212493 | 0.94 | SMN1; SMN2 (0.50) | MAPTALDH1A1LMNAUSP2HPGD | |
| SCHEMBL11506912 | 0.92 | SMN1; SMN2 (0.50) | MAPTALDH1A1LMNAUSP2HPGD | |
| SCHEMBL8394139 | 0.91 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAUSP2HPGD | |
| SCHEMBL9654341 | 0.86 | SMN1; SMN2 (0.52) | MAPTALDH1A1LMNAUSP2HPGD | |
| SCHEMBL2498213 | 0.86 | SMN1; SMN2 (0.60) | ALDH1A1LMNAUSP2HPGDMEN1 | |
| SCHEMBL2502591 | 0.86 | MTNR1A (0.52) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL12061827 | 0.86 | ALOX5 (0.48) | MAPTALDH1A1LMNAUSP2SMN1; SMN2 | |
| SCHEMBL10906771 | 0.86 | MAPT (0.49) | MAPTALDH1A1LMNAUSP2HPGD | |
| SCHEMBL8391475 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAUSP2HPGD | |
| SCHEMBL9651135 | 0.85 | MAPT (0.46) | MAPTALDH1A1LMNAUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627869-B1 | Vanilloid receptor modulators | AJINOMOTO KK (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-8168827-B2 | Amide derivative | AJINOMOTO CO., INC. (JP) | 2012-05-01 | — | — | US | disclosed |
| EP-2281823-A2 | Anti-inflammatory and analgesic piperidine derivatives | Ajinomoto Co., Inc. (JP) | 2011-02-09 | — | — | EP | disclosed |
| US-20090258900-A1 | AMIDE DERIVATIVE | AJINOMOTO CO. INC (JP) | 2009-10-15 | — | — | US | disclosed |
| US-7572815-B2 | Amide derivative | AJINOMOTO CO., INC. (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20060128755-A1 | Amide derivative | AJINOMOTO CO. INC (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1627869-A1 | AMIDE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128755-A1 | Amide derivative | NR0B1, NR0B2, NR1I3 | MAPT 4194/4885ALDH1A1 2684/4885LMNA 4454/4885 |
| US-20090258900-A1 | AMIDE DERIVATIVE | NR0B1, NR0B2, NR1I3 | MAPT 4315/4885ALDH1A1 2733/4885LMNA 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.