SCHEMBL10583192

SCHEMBL10583192

CS(=O)(=O)c1nc(Cl)c(S(C)(=O)=O)c(Cl)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 3/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TLR9 Q9NR96 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
HPGD P15428 1/20 0.31
GLP1R P43220 1/20 0.31
RIPK1 Q13546 1/20 0.30
BPTF Q12830 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9619744 0.82 ALDH1A1 (0.35) HTTALDH1A1MAPTL3MBTL1HPGD
SCHEMBL25859859 0.82 SMN1; SMN2 (0.41) SMN1; SMN2LMNAHTTNPC1ALDH1A1
SCHEMBL9626063 0.81 LMNA (0.34) SMN1; SMN2LMNAHTTNPC1ALDH1A1
SCHEMBL10123082 0.80 LMNA (0.40) SMN1; SMN2LMNAHTTNPC1ALDH1A1
SCHEMBL10957760 0.80 GLP1R (0.38) LMNAHTTALDH1A1MAPTL3MBTL1
SCHEMBL10482148 0.80 HTT (0.38) LMNAHTTALDH1A1MAPTL3MBTL1
SCHEMBL31513128 0.78 SMN1; SMN2 (0.39) SMN1; SMN2LMNAHTTNPC1ALDH1A1
SCHEMBL4806359 0.78 SMN1; SMN2 (0.39) SMN1; SMN2LMNAHTTNPC1ALDH1A1
SCHEMBL2960088 0.78 LMNA (0.39) SMN1; SMN2LMNAHTTNPC1ALDH1A1
Hydrochloric Acid SCHEMBL10583273 0.78 LMNA (0.32) SMN1; SMN2LMNAHTTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0321784-A2 Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials BAYER AG (DE) 1989-06-28 EP disclosed