Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dichloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichloroacetic Acid SCHEMBL31626281 | 1.00 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL8610682 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL2048740 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL7263072 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL8586625 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL6908140 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL108299 | 0.92 | — | — | |
| Dichloroacetic Acid SCHEMBL8610680 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL6913519 | 0.92 | LMNA (0.47) | — | |
| Dichloroacetic Acid SCHEMBL11098949 | 0.92 | LMNA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1553 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119955742-A | Culture medium for human metapneumovirus and application | 北京华诺泰生物医药科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| EP-4512393-A1 | COMBINATION OF SODIUM DICHLOROACETATE AND VALPROIC ACID SALTS FOR THE TREATMENT OF VIRAL AND BACTERIAL INFECTIONS AND INFLAMMATORY DISEASES | Lietuvos Sveikatos Mokslu Universitetas (LT) | 2025-02-26 | — | — | EP | claimed |
| WO-2025027522-A1 | METHODS, COMBINATIONS, AND COMPOSITIONS FOR CONTROLLING PEST | UPL MAURITIUS LIMITED (MU) | 2025-02-06 | — | — | WO | claimed |
| CN-115893369-B | Hard carbon negative electrode material, preparation method thereof, mixed negative electrode material and secondary battery | 赣州立探新能源科技有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119280309-A | NK cell extract-based composite preparation and anticancer application thereof | 深圳明杰生物工程有限公司 | 2025-01-10 | — | — | CN | claimed |
| US-20250015312-A1 | PLATINUM-CARBON CATALYST AND PREPARATION PROCESS AND USE THEREOF AND HYDROGEN FUEL CELL | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2025-01-09 | — | — | US | claimed |
| WO-2024255256-A1 | USE OF PYRUVATE DEHYDROGENASE KINASE INHIBITOR IN TREATMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION | 北京市心肺血管疾病研究所 | 2024-12-19 | — | — | WO | claimed |
| CN-118497132-B | Composition for improving CHO cell yield and regulating sugar type and application thereof | 苏州依科赛生物科技股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118791496-A | Preparation method of urotropine quaternary ammonium salt | 湖北三峡实验室 | 2024-10-18 | — | — | CN | claimed |
| CN-118745134-A | Method for removing impurities in betaine by electrodialysis method, betaine and application thereof | 黑龙江省拜尔杰医药科技有限公司 | 2024-10-08 | — | — | CN | claimed |
| EP-0444240-A1 | A method for classifying leukocytes and a reagent used therefor | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1991-09-04 | — | — | EP | claimed |
| US-4942268-A | HALOGENATION AN AROMATIC COMPOUND IN THE PRESENCE OF A ZEOLITE CATALYST | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-07-17 | — | — | US | claimed |
| US-4831199-A | CHLORINATION OF SUBSTITUTED BENZENES USING CATALYST OF ZEOLITE AND ALIPHATIC CARBOXYLIC ACID | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| EP-0154236-B1 | PROCESS FOR PRODUCING A HALOBENZENE | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1988-01-13 | — | — | EP | claimed |
| US-4686240-A | ALKALI OR ALKALINE EARTH METAL SALT OF A BRONSTED ACID | UNION CARBIDE CORPORATION (US) | 1987-08-11 | — | — | US | claimed |
| EP-0220697-A2 | Process for producing polyurethane foams using foam modifiers | UNION CARBIDE CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| US-4631294-A | TRAUMAS, STROKES, CARDIOVASCULAR DISORDERS | UNIVERSITY E.M., INC. (US) | 1986-12-23 | — | — | US | claimed |
| US-4558050-A | VITAMIN B1 DEPENDENT ENZYME STIMULATORS | UNIVERSITY OF FLORIDA (US) | 1985-12-10 | — | — | US | claimed |
| EP-0154236-A1 | Process for producing a halobenzene | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1985-09-11 | — | — | EP | claimed |
| US-4122188-A | Treatment of hyperlipoproteinemia with a dichloroacetate salt | VANDERBILT UNIVERSITY (US) | 1978-10-24 | — | — | US | claimed |