Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dichloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichloroacetic Acid SCHEMBL11098949 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL105849 | 0.92 | — | — | |
| Dichloroacetic Acid SCHEMBL11696458 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL9682655 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL8586625 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL6908140 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL108299 | 0.92 | — | — | |
| Dichloroacetic Acid SCHEMBL8610682 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL6913519 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 | |
| Dichloroacetic Acid SCHEMBL7263072 | 0.92 | LMNA (0.47) | LMNACA4CA1ALDH1A1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344626-A | Purification by removal of gases using carbon and salts such as carbonates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-06 | — | — | US | claimed |
| US-20250241299-A1 | Polymer Emulson Drift Reduction Adjuvant Formulations | ROSEN'S INC. | 2025-07-31 | — | — | US | disclosed |
| EP-3389848-B1 | METAL-CONTAINING SORBENTS FOR NITROGEN-CONTAINING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-109952148-B | Composite particles comprising metal-containing polymeric materials | 3M创新有限公司 | 2023-01-20 | — | — | CN | disclosed |
| US-11400433-B2 | Composite granules including metal-containing polymeric materials | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-08-02 | — | — | US | disclosed |
| CN-108472624-B | Metal-containing adsorbents for nitrogen-containing compounds | 3M创新有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20210346832-A1 | AIR FILTERS COMPRISING METAL-CONTAINING POLYMERIC SORBENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2021-11-11 | — | — | US | disclosed |
| CN-109922870-B | Air filter comprising metal-containing polymeric adsorbent | 3M创新有限公司 | 2021-11-02 | — | — | CN | disclosed |
| EP-3538246-B1 | AIR FILTERS COMPRISING METAL-CONTAINING POLYMERIC SORBENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3538260-B1 | COMPOSITE GRANULES INCLUDING METAL-CONTAINING POLYMERIC MATERIALS | 3M INNOVATIVE PROPERTIES CO (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2018089870-A1 | COMPOSITE GRANULES INCLUDING METAL-CONTAINING POLYMERIC MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20180105628-A1 | METAL-CONTAINING POLYMERIC MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY | 2018-04-19 | — | — | US | disclosed |
| EP-3298050-A1 | METAL-CONTAINING POLYMERIC MATERIALS | 3M Innovative Properties Company (US) | 2018-03-28 | — | — | EP | disclosed |
| WO-2016186858-A1 | METAL-CONTAINING POLYMERIC MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-11-24 | — | — | WO | disclosed |
| WO-1998031460-A1 | MULTI-GAS IMPREGNATED SORBENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-07-23 | — | — | WO | disclosed |
| EP-0647206-B1 | DUAL IMPREGNATED ACTIVATED CARBON | MINNESOTA MINING & MFG (US) | 1996-11-06 | — | — | EP | disclosed |
| US-5496785-A | MANUFACTURING IMPREGNATED ACTIVE CARBON FOR REMOVING GASEOUS CONTAMINANTS FROM A FLUID | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-03-05 | — | — | US | disclosed |
| EP-0647206-A1 | DUAL IMPREGNATED ACTIVATED CARBON. | MINNESOTA MINING & MFG (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5344626-A | Purification by removal of gases using carbon and salts such as carbonates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994000383-A1 | DUAL IMPREGNATED ACTIVATED CARBON | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-01-06 | — | — | WO | disclosed |