Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.67 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CLK2 | P49760 | 1/20 | 0.65 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | TOP2A | P11388 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636636 | 1.00 | MEN1 (0.72) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL5792107 | 0.92 | MEN1 (0.67) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL965845 | 0.91 | ALDH1A1 (0.70) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10695169 | 0.91 | ALDH1A1 (0.70) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL9522707 | 0.91 | ALDH1A1 (0.61) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL10511092 | 0.89 | MEN1 (0.63) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL968199 | 0.89 | KDM4E (0.82) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL968200 | 0.89 | KDM4E (0.82) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL6783172 | 0.89 | ALDH1A1 (0.81) | MEN1KMT2AKCNH2POLBCACNA1F | |
| SCHEMBL29593740 | 0.89 | ALDH1A1 (0.81) | MEN1KMT2AKCNH2POLBCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319906-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |