Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.81 |
| ▸ | HPGD | P15428 | 6/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.81 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | CLK2 | P49760 | 1/20 | 0.81 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.72 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29593740 | 1.00 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL9792010 | 0.92 | KCNH2 (0.79) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL3957125 | 0.92 | ALDH1A1 (0.79) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL8433684 | 0.92 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10352018 | 0.91 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL9485535 | 0.91 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| Hydrochloric Acid SCHEMBL10914782 | 0.91 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL8437432 | 0.90 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| (R)-Gatifloxacin SCHEMBL5670068 | 0.90 | KDM4E (1.00) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 | |
| SCHEMBL10401420 | 0.90 | ALDH1A1 (0.75) | ALDH1A1KDM4EHPGDKCNH2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60169475-A | — | — | None | — | — | JP | disclosed |
| EP-1401829-B1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2012-08-22 | — | — | EP | disclosed |
| US-6777420-B2 | A URACIL COMPOUNDS AS ENZYME INHIBITORS, INHIBIT BACTERIAL DNA POLYMERASE, TREATING BACTERIAL DISEASES | MICROBIOTIX, INC. | 2004-08-17 | — | — | US | disclosed |
| US-20030181719-A1 | Novel heterocyclic antibacterial compounds | MICROBIOTIX, INC. | 2003-09-25 | — | — | US | disclosed |
| US-5409933-A | Antibiotics | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-04-25 | — | — | US | disclosed |
| EP-0230295-B1 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN SEIYAKU KK (JP) | 1994-05-25 | — | — | EP | disclosed |
| WO-1993025545-A1 | NOVEL QUINOLINE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-23 | — | — | WO | disclosed |
| EP-0574231-A1 | Quinolone and naphthyridine derivatives having at the 3-position a group other than a carboxy group, as antibacterials | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-15 | — | — | EP | disclosed |
| EP-0337231-B1 | I. M. INJECTION FORMS OF GYRASE-INHIBITORS | BAYER AG (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-5043450-A | Bactericides | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5023257-A | Related to ciprofloxacin, in the form of oily suspension; bacterial infections | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |
| US-4980470-A | 8-alkoxyquinolonecarboxylic acid and salts thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0337231-A2 | I. M. injection forms of gyrase-inhibitors | BAYER AG (DE) | 1989-10-18 | — | — | EP | disclosed |
| EP-0126355-B1 | 7-AMINO-1-CYCLOPROPYL-6,8-DIFLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINE-CARBOXYLIC ACID, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1987-09-09 | — | — | EP | disclosed |
| EP-0230295-A2 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |
| EP-0178388-A1 | Quinolinecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-23 | — | — | EP | disclosed |
| JP-S60169475-A | QUINOLINE DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1985-09-02 | — | — | JP | disclosed |
| EP-0126355-A1 | 7-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid, processes for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181719-A1 | Novel heterocyclic antibacterial compounds | TOP1, TOP2A, TOP2B | ALDH1A1 2897/4885KDM4E 2689/4885HPGD 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.