Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319198 | 0.88 | SLC2A1 (0.48) | SLC2A1ADRB2RAD52PAX8ADRB1 | |
| SCHEMBL9764442 | 0.81 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764714 | 0.77 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| Hydrochloric Acid SCHEMBL9764518 | 0.76 | ADRB2 (0.52) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL1679989 | 0.74 | SLC2A1 (0.46) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764505 | 0.73 | SLC2A1 (0.50) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9321274 | 0.72 | ADRB3 (0.67) | ADRB2ADRB1ADRB3 | |
| SCHEMBL9764474 | 0.71 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764530 | 0.71 | SLC2A1 (0.48) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764439 | 0.70 | SLC2A1 (0.49) | SLC2A1ADRB2ADRB1ADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317206-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |