Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764442 | 0.92 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764714 | 0.89 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL10586259 | 0.88 | SLC2A1 (0.41) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| Hydrochloric Acid SCHEMBL9764518 | 0.88 | ADRB2 (0.52) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764505 | 0.85 | SLC2A1 (0.50) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764474 | 0.83 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764439 | 0.82 | SLC2A1 (0.49) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764530 | 0.82 | SLC2A1 (0.48) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL10417908 | 0.81 | SLC2A1 (0.55) | SLC2A1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL9764380 | 0.80 | ADRB2 (0.53) | SLC2A1ADRB2ADRB1ADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317206-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | claimed |
| US-5283262-A | Antiinflammatory, antiallergens | GLAXO GROUP LIMITED (GB) | 1994-02-01 | — | — | US | disclosed |
| US-5109023-A | For treating asthma, chronic bronchits, gastrointestinal disorders, anticoagulant, antiinflammatory agent and antiallergens | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5099068-A | Antiulcer agents, beta-adrenoreceptors or bronchodilator agents for treatment of asthma | GLAXO GROUP LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| US-4997986-A | Respiratory system disorders | GLAXO GROUP LIMITED (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0317206-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |