SCHEMBL10586325

SCHEMBL10586325

O=COC1CCC1Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6647394 0.90 HSD11B1 (0.39) GBA1
SCHEMBL8651297 0.84 GBA1 (0.37) GBA1
SCHEMBL8651985 0.67 GBA1 (0.40) GBA1
SCHEMBL25024091 0.66 NOS1 (0.44) GBA1
SCHEMBL29016930 0.66 GBA1 (0.55) GBA1
SCHEMBL23235646 0.66 GRM2 (0.44) GBA1
SCHEMBL28732114 0.66 GBA1 (0.53) GBA1
SCHEMBL10668078 0.66 KDM1A (0.49)
SCHEMBL28954933 0.65 POLB (0.52) GBA1
SCHEMBL11376939 0.65 DDB1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323536-A1 Arylcyclobutene/dienophile copolymers THE DOW CHEMICAL COMPANY (US) 1989-07-12 EP disclosed
US-4730030-A Arylcyclobutane/dienophile copolymer THE DOW CHEMICAL COMPANY (US) 1988-03-08 US disclosed