Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421185 | 0.84 | ATM (0.59) | CNR2ATMTDP1L3MBTL1PDK2 | |
| SCHEMBL10029708 | 0.83 | ATM (0.61) | CNR2ATMTDP1L3MBTL1PTGER1 | |
| SCHEMBL17950520 | 0.79 | ATM (0.75) | ATMTDP1L3MBTL1ITGB1ITGA2 | |
| SCHEMBL10745920 | 0.79 | CNR2 (0.49) | CNR2ATMTDP1L3MBTL1ITGB1 | |
| SCHEMBL3809549 | 0.78 | KMO (0.63) | PTGER1FNTAFNTBPTPRCALDH1A1 | |
| SCHEMBL10726242 | 0.77 | CNR2 (0.50) | CNR2ITGB1ITGA2LMNAHPGD | |
| SCHEMBL8426884 | 0.76 | MEN1 (0.49) | ATMLMNAHPGDSMN1; SMN2ALPG | |
| SCHEMBL209624 | 0.76 | ATM (0.67) | ATMTDP1L3MBTL1LMNAHPGD | |
| SCHEMBL17068941 | 0.76 | ALDH1A1 (0.70) | ATMTDP1L3MBTL1LMNAHPGD | |
| SCHEMBL251921 | 0.76 | ALDH1A1 (0.70) | ATMTDP1L3MBTL1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322151-A2 | Aromatic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-06-28 | — | — | EP | disclosed |