Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | UBE2M | P61081 | 2/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802288 | 0.87 | DCUN1D1 (0.66) | SLC6A9SLC6A5ALDH1A1AGERUBE2M | |
| SCHEMBL10587267 | 0.87 | SLC6A9 (0.61) | SLC6A9SLC6A5POLBTP53SMN1; SMN2 | |
| SCHEMBL11621624 | 0.86 | AGER (0.64) | SLC6A9SLC6A5TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9257544 | 0.85 | SLC6A9 (0.59) | SLC6A9SLC6A5POLBTP53SMN1; SMN2 | |
| SCHEMBL23200143 | 0.85 | MEN1 (0.62) | POLBTP53SMN1; SMN2ALDH1A1MAPT | |
| Pencycuron SCHEMBL22525 | 0.85 | AGER (0.62) | SLC6A9SLC6A5TP53SMN1; SMN2ALDH1A1 | |
| Pencycuron SCHEMBL8817027 | 0.85 | AGER (0.62) | SLC6A9SLC6A5TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL23200125 | 0.84 | SLC6A9 (0.55) | SLC6A9SLC6A5POLBTP53SMN1; SMN2 | |
| SCHEMBL23200115 | 0.82 | TSHR (0.55) | SLC6A9SLC6A5POLBTP53SMN1; SMN2 | |
| SCHEMBL23200085 | 0.81 | SMN1; SMN2 (0.66) | POLBTP53SMN1; SMN2ALDH1A1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325397-A1 | Diurea derivatives useful as medicaments and processes for the preparation thereof | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |