Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.61 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.61 |
| ▸ | AGER | Q15109 | 1/20 | 0.57 |
| ▸ | UBE2M | P61081 | 6/20 | 0.56 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621624 | 0.94 | AGER (0.64) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| Pencycuron SCHEMBL22525 | 0.92 | AGER (0.62) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| Pencycuron SCHEMBL8817027 | 0.92 | AGER (0.62) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| SCHEMBL7802288 | 0.92 | DCUN1D1 (0.66) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| SCHEMBL19570417 | 0.91 | CCR1 (0.56) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| SCHEMBL23200170 | 0.90 | SLC6A9 (0.54) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| SCHEMBL9257544 | 0.90 | SLC6A9 (0.59) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| SCHEMBL10587249 | 0.87 | SLC6A9 (0.58) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| Pencycuron SCHEMBL16931548 | 0.86 | AGER (0.55) | SLC6A9SLC6A5AGERUBE2MDCUN1D1 | |
| SCHEMBL11447172 | 0.84 | POLB (0.59) | AGERSMN1; SMN2ALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325397-A1 | Diurea derivatives useful as medicaments and processes for the preparation thereof | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |