SCHEMBL10587263

SCHEMBL10587263

CP(=O)(O)C(CCN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 2/20 0.54
GABBR1 Q9UBS5 2/20 0.54
GABRR1 P24046 3/20 0.46
FOLH1 Q04609 1/20 0.42
CYP1A2 P05177 1/20 0.41
TSHR P16473 1/20 0.41
THPO P40225 1/20 0.41
LMNA P02545 1/20 0.40
BLM P54132 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
GGH Q92820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10491234 0.98 GABBR2 (0.52) GABBR2GABBR1GABRR1FOLH1CYP1A2
SCHEMBL6882285 0.82 FOLH1 (0.61) GABBR2GABBR1GABRR1FOLH1LMNA
SCHEMBL4341072 0.75 FOLH1 (0.41) FOLH1GRIN2DGRIN3BGRIN1GRIN2A
Ammonia Solution, Strong SCHEMBL27862237 0.73 FOLH1 (0.40) FOLH1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL10694985 0.71 GABBR2 (0.50) GABBR2GABBR1GABRR1CYP1A2TSHR
SCHEMBL341289 0.70
SCHEMBL341418 0.70
SCHEMBL9115882 0.70 FOLH1 (0.42) GABBR2GABBR1GABRR1FOLH1LMNA
SCHEMBL4726591 0.70 FOLH1 (0.57) FOLH1LMNABLM
SCHEMBL2978558 0.68 CHRM1 (0.48) FOLH1GGH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55064595-A None JP disclosed
JP-1233203-A None JP disclosed
JP-H01233203-A HERBICIDE COMPOSITION MITSUBISHI PETROCHEM CO LTD 1989-09-19 JP disclosed
JP-S5564595-A PREPARATION OF ALPHA-AMINO-ALPHA-CARBOXYPROPYL-METHYLPHOSPHINIC ACID OR ITS SALT NISSAN CHEM IND LTD 1980-05-15 JP disclosed