Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589428 | 1.00 | SLC1A3 (0.41) | SLC1A3SLC1A2SLC1A1LTA4HREN | |
| SCHEMBL10588898 | 0.89 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1LTA4HREN | |
| SCHEMBL7291539 | 0.86 | REN (0.53) | SLC1A3SLC1A2SLC1A1LTA4HREN | |
| SCHEMBL10433749 | 0.86 | REN (0.53) | SLC1A3SLC1A2SLC1A1LTA4HREN | |
| SCHEMBL9177605 | 0.86 | REN (0.53) | SLC1A3SLC1A2SLC1A1LTA4HREN | |
| SCHEMBL21197392 | 0.83 | LTA4H (0.44) | SLC1A3SLC1A2SLC1A1LTA4HCPB2 | |
| SCHEMBL28948924 | 0.83 | LTA4H (0.44) | SLC1A3SLC1A2SLC1A1LTA4HCPB2 | |
| SCHEMBL22580186 | 0.78 | LTA4H (0.43) | SLC1A3SLC1A2SLC1A1LTA4HREN | |
| SCHEMBL10587538 | 0.76 | REN (0.54) | RENCTSK | |
| SCHEMBL4196007 | 0.75 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1LTA4HCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329295-A1 | Renin inhibiting peptides with polar end groups | THE UPJOHN COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |