Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586024 | 0.95 | KDM4E (0.39) | KDM4EALDH1A1MAPTL3MBTL1RXFP1 | |
| SCHEMBL10587828 | 0.94 | KDM4E (0.39) | KDM4EALDH1A1MAPTL3MBTL1RXFP1 | |
| SCHEMBL10586818 | 0.91 | KDM4E (0.37) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL3875987 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL421735 | 0.85 | KDM4E (0.40) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL10584563 | 0.79 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL10586910 | 0.78 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL2594812 | 0.77 | KMT2A (0.40) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL10584621 | 0.77 | KDM4E (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL13692648 | 0.77 | SMN1; SMN2 (0.39) | KDM4EALDH1A1MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302401-A1 | Pyridone dyes, process for their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |