Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159354 | 0.88 | MEN1 (0.41) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL421735 | 0.85 | KDM4E (0.40) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL3875987 | 0.84 | KDM4E (0.44) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL14694502 | 0.82 | L3MBTL1 (0.35) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL10586818 | 0.78 | KDM4E (0.37) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10586024 | 0.77 | KDM4E (0.39) | ALDH1A1MAPTRECQLL3MBTL1GAA | |
| SCHEMBL10587384 | 0.77 | KDM4E (0.36) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL13692648 | 0.77 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10587828 | 0.76 | KDM4E (0.39) | ALDH1A1MAPTRECQLL3MBTL1GAA | |
| SCHEMBL13931148 | 0.75 | HTT (0.39) | KMT2AMEN1ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566848-A1 | IMPROVED OLIGOTHIOPHENES | Commonwealth Scientific and Industrial Research Organisation (AU) | 2013-03-13 | — | — | EP | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| WO-2011137487-A1 | IMPROVED OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011137487-A1 | IMPROVED OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130042918-A1 | OLIGOTHIOPHENES | NR0B2, NR2C2, NR1H2 | KMT2A 2144/4885MEN1 2968/4885ALDH1A1 1604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.