Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961242 | 0.82 | HMGCR (0.43) | MAPK14PRKCZGCGRKDM4EL3MBTL1 | |
| SCHEMBL6961105 | 0.80 | GCGR (0.50) | GCGR | |
| SCHEMBL6953892 | 0.76 | GCGR (0.61) | GCGR | |
| SCHEMBL10589454 | 0.75 | TP53 (0.43) | GCGRKDM4EALDH1A1 | |
| SCHEMBL6961920 | 0.75 | GCGR (0.51) | GCGR | |
| SCHEMBL6962775 | 0.73 | GCGR (0.48) | GCGR | |
| SCHEMBL9410045 | 0.73 | GCGR (0.50) | GCGR | |
| SCHEMBL6963303 | 0.72 | GCGR (0.50) | GCGR | |
| SCHEMBL6958555 | 0.72 | GCGR (0.61) | GCGR | |
| SCHEMBL6958411 | 0.72 | GCGR (0.40) | GCGRKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325130-A2 | Substituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |