Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19704645 | 0.86 | GSTP1 (0.40) | LMNAHSD17B10POLBGSTP1GSTM2 | |
| SCHEMBL8675041 | 0.81 | APOBEC3G (0.46) | LMNAHSD17B10POLBGSTP1GSTM2 | |
| SCHEMBL7776841 | 0.81 | HSD17B10 (0.72) | LMNAHSD17B10POLBALDH1A1MAPT | |
| SCHEMBL15123545 | 0.80 | ABL1 (0.48) | LMNAHSD17B10POLBGSTP1GSTM2 | |
| SCHEMBL2116085 | 0.80 | CYP1A2 (0.54) | LMNAHSD17B10POLBGSTP1GSTM2 | |
| SCHEMBL5300204 | 0.79 | KDM4E (0.54) | LMNAHSD17B10POLBGSTP1GSTM2 | |
| SCHEMBL22226782 | 0.79 | MAPT (0.50) | LMNAHSD17B10GSTP1GSTM2ALDH1A1 | |
| SCHEMBL9701297 | 0.79 | MEN1 (0.54) | HSD17B10POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28897181 | 0.77 | CYP1A2 (0.59) | LMNAPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL8158427 | 0.75 | HSD17B10 (0.49) | HSD17B10POLBALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342902-A2 | 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | claimed |