Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | FGB | P02675 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethylbenzene SCHEMBL9765749 | 0.87 | POLB (0.45) | MEN1KMT2APOLBFGBALDH1A1 | |
| Succinic Acid SCHEMBL11703500 | 0.87 | POLB (0.46) | MEN1KMT2APOLBFGBALDH1A1 | |
| SCHEMBL27583379 | 0.80 | POLB (0.47) | MEN1KMT2APOLBFGBALDH1A1 | |
| SCHEMBL7402835 | 0.80 | CYP1A2 (0.63) | MEN1KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL5143206 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2APOLBFGBALDH1A1 | |
| SCHEMBL13125 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2APOLBFGBALDH1A1 | |
| SCHEMBL11603953 | 0.79 | HTR7 (0.51) | MEN1KMT2APOLBFGBALDH1A1 | |
| SCHEMBL21189320 | 0.79 | CYP1A2 (0.68) | POLBALDH1A1HSD17B10CYP2C19MAPT | |
| SCHEMBL5637483 | 0.79 | SMN1; SMN2 (0.56) | MEN1KMT2APOLBFGBALDH1A1 | |
| SCHEMBL14557238 | 0.79 | MAP2K7 (0.49) | MEN1KMT2APOLBFGBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342902-A2 | 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | claimed |
| EP-0342904-A2 | 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | claimed |
| EP-3508484-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-07-10 | — | — | EP | disclosed |
| US-5081240-A | PROCESS FOR THE PREPARATION OF BENZOTHIAZEPIN-ONE DERIVATIVES | SANOFI (FR) | 1992-01-14 | — | — | US | disclosed |
| EP-0342902-A2 | 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0342904-A2 | 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem | MARION LABORATORIES, INC. (a Delaware corporation) (US) | 1989-11-23 | — | — | EP | disclosed |