Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840587 | 0.85 | CYP4F2 (0.61) | APOBEC3GPOLBTSHRCYP4F2CYP4A11 | |
| SCHEMBL10588609 | 0.81 | LMNA (0.47) | HSD17B10POLBGSTP1GSTM2MTNR1A | |
| SCHEMBL2116085 | 0.80 | CYP1A2 (0.54) | HSD17B10POLBGSTP1GSTM2ALDH1A1 | |
| SCHEMBL7776841 | 0.78 | HSD17B10 (0.72) | HSD17B10POLBTSHRALDH1A1HPGD | |
| SCHEMBL10175060 | 0.75 | PTGS2 (0.51) | HSD17B10POLBTSHRMTNR1AMTNR1B | |
| SCHEMBL10504984 | 0.75 | HSD17B10 (0.59) | HSD17B10POLBTSHRCYP4F2CYP4A11 | |
| SCHEMBL28897181 | 0.75 | CYP1A2 (0.59) | POLBTSHRMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL26942237 | 0.74 | APOBEC3G (0.57) | APOBEC3GALDH1A1PTGS2 | |
| SCHEMBL12255257 | 0.73 | PTGS2 (0.55) | HSD17B10POLBTSHRALDH1A1HPGD | |
| SCHEMBL17045927 | 0.73 | EPHX2 (0.52) | HSD17B10POLBMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789584-A | Substituted-pyridinyl cephalosporin antibiotics active against methicillin resistant bacteria | MICROCIDE PHARMACEUTICALS, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5756493-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| US-5698547-A | 7-(ACYLAMINO)-3-(ARYLTHIO)-3-CEPHEM-4-CARBOXYLIC ACIDS WHICH EXHIBIT ANTIBACTERIAL ACTIVITY AGAINST ORGANISMS RESISTANT TO BETA-LACTAM ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |
| EP-0754184-A1 | CEPHALOSPORIN ANTIBIOTICS | Microcide Pharmaceuticals, Inc. (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5593986-A | Cephalosporin antibiotics | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996038450-A1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| WO-1995026966-A1 | CEPHALOSPORIN ANTIBIOTICS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |