SCHEMBL10590262

SCHEMBL10590262

C=CC=CC=Cc1ccccc1.N#CC=COC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.40
MAOB P27338 6/20 0.38
HDAC3 O15379 2/20 0.38
HDAC4 P56524 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC10 Q969S8 2/20 0.38
HDAC11 Q96DB2 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
HDAC9 Q9UKV0 2/20 0.38
HDAC5 Q9UQL6 2/20 0.38
LMNA P02545 5/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL157051 0.83 ALDH1A1 (0.42) MCL1HDAC3HDAC4HDAC1HDAC7
Acrylonitrile SCHEMBL8912106 0.81 MAOB (0.47) MCL1MAOBHDAC3HDAC4HDAC1
SCHEMBL9817383 0.81 MAOB (0.50) MCL1MAOBHDAC3HDAC4HDAC1
SCHEMBL7159537 0.81 MAOB (0.50) MCL1MAOBHDAC3HDAC4HDAC1
SCHEMBL8948870 0.81 MAOB (0.50) MCL1MAOBHDAC3HDAC4HDAC1
SCHEMBL8777869 0.80 HDAC3 (0.45) MCL1MAOBHDAC3HDAC4HDAC1
Styrene SCHEMBL5130055 0.79 ALDH1A1 (0.41) MCL1HDAC3HDAC4HDAC1HDAC7
Acrylic Acid SCHEMBL4433225 0.79 MCL1 (0.44) MCL1MAOBHDAC3HDAC4HDAC1
Acrylonitrile SCHEMBL10482347 0.78 LMNA (0.40) MCL1MAOBHDAC3HDAC4HDAC1
Acrylonitrile SCHEMBL18347 0.77 MAOB (0.54) MCL1MAOBHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190247616-A1 Connection System For Tunneled Catheters BARD INC C R (US) 2019-08-15 US claimed
US-10272227-B2 Connection system for tunneled catheters C. R. BARD, INC. (US) 2019-04-30 US claimed
US-10252453-B2 Resin molded article, method for manufacturing the same, and printer CANON KABUSHIKI KAISHA (JP) 2019-04-09 US claimed
EP-3215211-A1 CONNECTION SYSTEM FOR TUNNELED CATHETERS C. R. BARD, INC. (US) 2017-09-13 EP claimed
US-20160129222-A1 Connection System for Tunneled Catheters C. R. BARD, INC. 2016-05-12 US claimed
WO-2016073954-A1 CONNECTION SYSTEM FOR TUNNELED CATHETERS C. R. BARD, INC. (US) 2016-05-12 WO claimed
WO-2024137341-A1 NOVEL COMPATIBILIZER COMPOSITIONS AND BLENDS THEREOF Jabil Inc. (US) 2024-06-27 WO disclosed
US-11017191-B2 Accessory having a target generating structure for a mobile device THE CODE CORPORATION (US) 2021-05-25 US disclosed
CN-112639173-A Coated substrate and method for producing the same PPG工业俄亥俄公司 2021-04-09 CN disclosed
US-20190228197-A1 BARCODE-READING ENHANCEMENT SYSTEM FOR A COMPUTING DEVICE THAT COMPRISES A CAMERA AND AN ILLUMINATION SYSTEM THE CODE CORPORATION 2019-07-25 US disclosed
US-10272227-B2 Connection system for tunneled catheters C. R. BARD, INC. (US) 2019-04-30 US disclosed
US-10252453-B2 Resin molded article, method for manufacturing the same, and printer CANON KABUSHIKI KAISHA (JP) 2019-04-09 US disclosed
US-10248821-B2 Target generating structure for an accessory for a mobile device THE CODE CORPORATION (US) 2019-04-02 US disclosed
US-20160129222-A1 Connection System for Tunneled Catheters C. R. BARD, INC. 2016-05-12 US disclosed
WO-2016073954-A1 CONNECTION SYSTEM FOR TUNNELED CATHETERS C. R. BARD, INC. (US) 2016-05-12 WO disclosed
US-20150220766-A1 BARCODE-READING ENHANCEMENT SYSTEM FOR A COMPUTING DEVICE THAT COMPRISES A CAMERA AND AN ILLUMINATION SYSTEM THE CODE CORPORATION 2015-08-06 US disclosed
US-20150044407-A1 COMPOSITE VESSELS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-12 US disclosed
CN-100509954-C Non halogenic, low smoky fire retardant polycarbonate/resin of acrylonitrile butylbenzene and preparation method thereof SHANGHAI KINGFA SCI & TECH CO (CN) 2009-07-08 CN disclosed
CN-1696195-A Non halogenic, low smoky fire retardant polycarbonate/resin of acrylonitrile butylbenzene and preparation method JINFA TECH DEV CO LTD SHANGHAI (CN) 2005-11-16 CN disclosed
EP-0333694-A2 Polybrominated phenylphosphate flame retardant thermoplastic composition FMC Corporation (US) 1989-09-20 EP disclosed