Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11964484 | 0.74 | TDP1 (0.49) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL15561472 | 0.74 | TDP1 (0.49) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL9064462 | 0.74 | TDP1 (0.49) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL461207 | 0.74 | CASP3 (0.44) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL4624003 | 0.74 | TDP1 (0.49) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL4623781 | 0.74 | TDP1 (0.49) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL3259474 | 0.74 | CASP3 (0.44) | CASP3ALDH1A1TDP1TSHRLMNA | |
| SCHEMBL10590544 | 0.73 | LMNA (0.46) | CASP3ALDH1A1TSHRLMNAGAA | |
| SCHEMBL8971961 | 0.73 | NPSR1 (0.45) | CASP3ALDH1A1TSHRLMNAGAA | |
| SCHEMBL4715603 | 0.72 | TDP1 (0.50) | CASP3ALDH1A1TDP1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304018-A2 | Process for the preparation of aryl-(1-phthalimido)alkyl ketones | Degussa Aktiengesellschaft (DE) | 1989-02-22 | — | — | EP | disclosed |