Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801124 | 0.84 | ERCC1 (0.53) | LMNAALDH1A1GAAKDM4ECYP3A4 | |
| SCHEMBL20877620 | 0.79 | CASP3 (0.41) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL20877618 | 0.79 | CASP3 (0.41) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL10590544 | 0.78 | LMNA (0.46) | CASP3LMNAALDH1A1GAAPOLB | |
| SCHEMBL9385741 | 0.77 | TDP1 (0.50) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL27338868 | 0.77 | LMNA (0.52) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL5696780 | 0.76 | LMNA (0.50) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL7551296 | 0.76 | LMNA (0.50) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL11964484 | 0.76 | TDP1 (0.49) | TDP1CASP3LMNAALDH1A1GAA | |
| SCHEMBL4623781 | 0.76 | TDP1 (0.49) | TDP1CASP3LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8337591-A | — | — | None | — | — | JP | disclosed |
| CN-113045477-B | Preparation method of fluorine-containing primary amine intermediate | 中蓝晨光化工研究设计院有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-113045477-A | Preparation method of fluorine-containing primary amine intermediate | 中蓝晨光化工研究设计院有限公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-2794622-B1 | PROTECTED LINKER COMPOUNDS | RESEACHEM GMBH (CH) | 2018-08-08 | — | — | EP | disclosed |
| US-9534003-B2 | Protected linker compounds | RESEACHEM GMBH (CH) | 2017-01-03 | — | — | US | disclosed |
| WO-2015065212-A1 | NOVEL N3-AMINOALKYL DERIVATIVES OF 5-ARYLIDENEHYDANTOIN, PHARMACEUTICAL COMPOSITION CONTAINING THE ABOVE AND APPLICATION THEREOF | Uniwersytet Jagielloński (PL) | 2015-05-07 | — | — | WO | disclosed |
| US-20150011746-A1 | Protected Linker Compounds | RESEACHEM GMBH (CH) | 2015-01-08 | — | — | US | disclosed |
| EP-2794622-A1 | PROTECTED LINKER COMPOUNDS | Reseachem GmbH (CH) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013091120-A1 | PROTECTED LINKER COMPOUNDS | RESEACHEM GMBH (CH) | 2013-06-27 | — | — | WO | disclosed |
| JP-H08337591-A | GLYCOSYL OXYALKYLAMINE AND ITS PRODUCTION | D D S KENKYUSHO:KK | 1996-12-24 | — | — | JP | disclosed |
| US-4211703-A | CHEMICAL INTERMEDIATES FOR CEPHALOSPORINS | SMITHKLINE CORPORATION (US) | 1980-07-08 | — | — | US | disclosed |
| US-4189573-A | CHEMICAL INTERMEDIATES | SMITHKLINE CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |
| US-4112086-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4106940-A | N-ALKYLPHTHALIMIDE DERIVATIVE OIL FORMER | AGFA-GEVAERT, A.G. (DE) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011746-A1 | Protected Linker Compounds | RNGTT, PHAX, CPSF1 | TDP1 596/4885CASP3 2975/4885LMNA 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.