Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13955312 | 0.79 | CA12 (0.41) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL3073635 | 0.78 | GRIN2D (0.40) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL1793798 | 0.76 | EPHX1 (0.39) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL20315917 | 0.76 | CA12 (0.39) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL15723556 | 0.76 | EPHX1 (0.39) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL10590297 | 0.75 | — | — | |
| SCHEMBL10488628 | 0.74 | ALDH1A1 (0.52) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL15721351 | 0.74 | DNM1 (0.39) | CA1CA12CA9CA2SPHK2 | |
| SCHEMBL6846178 | 0.74 | CA12 (0.42) | CA1CA12CA9ALDH1A1ALDH2 | |
| SCHEMBL28417961 | 0.74 | CA12 (0.41) | CA1CA12CA9ALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0339496-A2 | Aminoguanidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-11-02 | — | — | EP | claimed |