SCHEMBL1059262

SCHEMBL1059262

O=C(O)CC(=O)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.47
SRR Q9GZT4 1/20 0.47
PLOD2 O00469 3/20 0.41
CES1 P23141 6/20 0.41
PLOD3 O60568 2/20 0.40
PLOD1 Q02809 2/20 0.40
FAAH O00519 8/20 0.39
ACLY P53396 2/20 0.39
CES2 O00748 2/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CA2 P00918 1/20 0.36
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14973493 0.97 LDHA (0.44) LDHASRRPLOD2CES1PLOD3
SCHEMBL8645726 0.97 LDHA (0.44) LDHASRRPLOD2CES1PLOD3
SCHEMBL7544594 0.97 LDHA (0.44) LDHASRRPLOD2CES1PLOD3
Hydrochloric Acid SCHEMBL7501867 0.97 LDHA (0.44) LDHASRRPLOD2CES1PLOD3
Water SCHEMBL7191917 0.87 PLOD2 (0.44) PLOD2CES1PLOD3PLOD1FAAH
Water SCHEMBL7197275 0.87 PLOD2 (0.44) PLOD2CES1PLOD3PLOD1FAAH
SCHEMBL28749515 0.86 LDHA (0.40) LDHASRRPLOD2CES1PLOD3
SCHEMBL183178 0.83 PLOD2 (0.46) PLOD2CES1PLOD3PLOD1FAAH
SCHEMBL6517983 0.80 PLOD2 (0.44) PLOD2CES1PLOD3PLOD1FAAH
SCHEMBL9326020 0.80 PLOD2 (0.44) PLOD2CES1PLOD3PLOD1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES ADAMA AGAN LTD (IL) 2025-04-10 US claimed
EP-4025653-B1 STAIN RESISTANT ADDITIVE ARXADA AG (CH) 2023-11-15 EP claimed
EP-4232028-A1 METHODS OF MAKING NICOTINIC ACID DERIVATIVES Vertellus Holdings LLC (US) 2023-08-30 EP claimed
WO-2023017518-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES ADAMA AGAN LTD. (IL) 2023-02-16 WO claimed
CN-107876092-B Application of titanium catalyst with cyclic structure as reaction catalyst for synthesizing benzyl carbonate or diphenyl carbonate by ester exchange 华东理工大学 2023-01-10 CN claimed
CN-112899246-B Aldehyde ketone reductase KmAKR mutant and application thereof in catalytic synthesis of chiral alcohol 浙江工业大学 2022-06-21 CN claimed
EP-3486241-B1 METHOD FOR PRODUCING CRYSTAL OF URACIL COMPOUND SUMITOMO CHEMICAL CO (JP) 2022-05-04 EP claimed
WO-2022087373-A1 METHODS OF MAKING NICOTINIC ACID DERIVATIVES VERTELLUS HOLDINGS LLC (US) 2022-04-28 WO claimed
EP-2247577-B2 METHOD FOR THE REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES BAYER IP GMBH (DE) 2022-04-27 EP claimed
CN-114195714-A Simple synthesis method of celecoxib 山东铂源药业有限公司 2022-03-18 CN claimed
EP-0448544-B1 Process for preparation of fluoromethyl-substituted piperidine carbodithioates ROHM & HAAS (US) 1996-07-03 EP claimed
EP-0546669-B1 Preparation of fluorine-doped tungstic oxide and glass coating process FORD MOTOR CO (GB) 1996-04-17 EP claimed
EP-0599036-A1 Method for the preparation of 2-aryl-5-trifluoromethyl pyrrole compounds AMERICAN CYANAMID COMPANY (US) 1994-06-01 EP claimed
EP-0448544-A2 Process for preparation of fluoromethyl-substituted piperidine carbodithioates ROHM AND HAAS COMPANY (US) 1991-09-25 EP claimed
US-5039753-A Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) LTD (IE) 1991-08-13 US claimed
EP-0313387-A2 Polymers comprising betadiketone groups and polymerizable compositions containing said polymers LOCTITE (IRELAND) Ltd. (IE) 1989-04-26 EP claimed
EP-0135491-B1 HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS MONSANTO COMPANY (US) 1989-01-25 EP claimed
EP-0158399-B1 LIQUID COATING COMPOSITION FOR PRODUCING HIGH QUALITY, HIGH PERFORMANCE FLUORINE-DOPED TIN OXIDE COATINGS M & T CHEMICALS, INC. (US) 1988-11-02 EP claimed
EP-0206953-B1 PROCESS FOR THE PREPARATION OF ETHYL TRIFLUOROACETOACETATE RHONE-POULENC CHIMIE (FR) 1988-09-07 EP claimed
EP-0206953-A1 Process for the preparation of ethyl trifluoroacetoacetate RHONE-POULENC CHIMIE (FR) 1986-12-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES DPYD, PDK1, CYP2S1 LDHA 386/4885SRR 1411/4885PLOD2 3669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.