Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 11/20 | 0.38 |
| ▸ | METAP1 | P53582 | 8/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592799 | 1.00 | METAP2 (0.38) | METAP2METAP1RENSMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10591722 | 0.99 | METAP2 (0.37) | METAP2METAP1RENSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7355135 | 0.99 | METAP2 (0.37) | METAP2METAP1RENSMN1; SMN2 | |
| SCHEMBL7385184 | 0.76 | REN (0.39) | METAP2METAP1REN | |
| SCHEMBL7385187 | 0.76 | REN (0.39) | METAP2METAP1REN | |
| SCHEMBL7273148 | 0.76 | REN (0.39) | METAP2METAP1REN | |
| SCHEMBL7280466 | 0.76 | REN (0.39) | METAP2METAP1REN | |
| SCHEMBL7280572 | 0.76 | REN (0.39) | METAP2METAP1REN | |
| SCHEMBL7287797 | 0.76 | METAP2 (0.38) | METAP2METAP1REN | |
| SCHEMBL10590988 | 0.76 | METAP2 (0.38) | METAP2METAP1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |