SCHEMBL10593124

SCHEMBL10593124

C=CCN1CCCC(O[N+](=O)[O-])C1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
PKM P14618 1/20 0.31
GSR P00390 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10591825 0.81 GSR (0.32) GSR
Nitric Acid SCHEMBL10593117 0.74 ALDH1A1 (0.39) DRD2DRD3CYP1A2CYP2D6CYP2C9
SCHEMBL8523613 0.73 BCHE (0.40) DRD2DRD3CYP1A2CYP2D6KDM4E
SCHEMBL3756225 0.73 CYP3A4 (0.38) DRD2DRD3CYP1A2CYP2D6KDM4E
SCHEMBL3757483 0.73 CYP3A4 (0.38) DRD2DRD3CYP1A2CYP2D6KDM4E
Formic Acid SCHEMBL31266947 0.73 DRD2 (0.35) DRD2DRD3CYP1A2CYP2D6CYP3A4
SCHEMBL3756230 0.73 CYP3A4 (0.38) DRD2DRD3CYP1A2CYP2D6KDM4E
SCHEMBL9330338 0.70 SMN1; SMN2 (0.45) CYP2D6CYP3A4GSR
SCHEMBL4056755 0.70 DRD3 (0.41) DRD2DRD3
SCHEMBL10592932 0.68 GSR (0.34) GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4405334-A 1-ALKYLPIPERIDINOL NITRATE ESTER ANTIKNOCK ADDITIVE ETHYL CORPORATION (US) 1983-09-20 US claimed
EP-0338599-A2 Diesel fuel composition ETHYL CORPORATION (US) 1989-10-25 EP disclosed
EP-0195462-A2 Diesel fuel composition ETHYL CORPORATION (US) 1986-09-24 EP disclosed
EP-0101093-A2 Diesel fuel composition ETHYL CORPORATION (US) 1984-02-22 EP disclosed
US-4405334-A 1-ALKYLPIPERIDINOL NITRATE ESTER ANTIKNOCK ADDITIVE ETHYL CORPORATION (US) 1983-09-20 US disclosed