Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL815759 | 0.79 | ACHE (0.44) | ACHENOTUMMAPTHPGD | |
| SCHEMBL9866519 | 0.74 | NOTUM (0.31) | NOTUM | |
| SCHEMBL5951677 | 0.68 | ACHE (0.47) | ACHESRD5A1 | |
| SCHEMBL5951943 | 0.66 | ACHE (0.46) | ACHE | |
| SCHEMBL817973 | 0.65 | ACHE (0.46) | ACHE | |
| SCHEMBL5953125 | 0.65 | ACHE (0.41) | ACHEMAPT | |
| SCHEMBL25469311 | 0.64 | — | — | |
| SCHEMBL29404958 | 0.63 | METAP1 (0.56) | ACHESRD5A1 | |
| SCHEMBL30666550 | 0.63 | ACHE (0.66) | ACHESRD5A1 | |
| SCHEMBL6248819 | 0.63 | METAP1 (0.56) | ACHESRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | claimed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |