Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 6/20 | 0.38 |
| ▸ | NOS3 | P29474 | 5/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523909 | 0.76 | KMT2A (0.41) | KMT2ANOS2NOS3CES1 | |
| SCHEMBL19129357 | 0.76 | KMT2A (0.41) | KMT2ANOS2NOS3CES1 | |
| SCHEMBL11536198 | 0.76 | KMT2A (0.42) | ACHEKMT2ANOS2NOS3CES1 | |
| SCHEMBL11533284 | 0.76 | KMT2A (0.49) | ACHEKMT2ANOS2NOS3 | |
| SCHEMBL9865445 | 0.72 | KMT2A (0.42) | KMT2ANOS2NOS3 | |
| SCHEMBL14127907 | 0.71 | NOS2 (0.35) | ACHEKMT2ANOS2NOS3 | |
| SCHEMBL14024432 | 0.70 | — | — | |
| SCHEMBL8350640 | 0.70 | — | — | |
| SCHEMBL9865556 | 0.69 | ACHE (0.47) | ACHENOS2NOS3CES1 | |
| SCHEMBL19135958 | 0.68 | KMT2A (0.41) | ACHEKMT2ANOS2NOS3CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673178-B2 | Liquid crystal medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-08-09 | — | — | US | disclosed |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-08-09 | — | — | US | disclosed |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-08-09 | — | — | US | disclosed |
| US-8173828-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173828-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-8173828-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| WO-2007028536-A2 | PROCESS FOR PREPARING OLEFIN POLYMERS IN THE PRESENCE OF CATALYST SYSTEMS HAVING PHOTOCHROMIC GROUPS | BASELL POLYOLEFINE GMBH (DE) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007028536-A2 | PROCESS FOR PREPARING OLEFIN POLYMERS IN THE PRESENCE OF CATALYST SYSTEMS HAVING PHOTOCHROMIC GROUPS | BASELL POLYOLEFINE GMBH (DE) | 2007-03-15 | — | — | WO | disclosed |
| EP-1327636-B1 | Heterocyclic metallocenes and polymerisation catalysts | BASELL POLYOLEFINE GMBH (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-20050192418-A1 | Heterocyclic metallocenes and polymerization catalysts | EQUISTAR CHEMICALS, LP | 2005-09-01 | — | — | US | disclosed |
| EP-1327636-A2 | Heterocyclic metallocenes and polymerisation catalysts | Basell Polyolefine GmbH (DE) | 2003-07-16 | — | — | EP | disclosed |
| EP-0938491-B1 | HETEROCYCLIC METALLOCENES AND POLYMERIZATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | OPRM1, POLM, AP1M1 | ACHE 3852/4885KMT2A 895/4885NOS2 3571/4885 |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | ACHE 3416/4885KMT2A 2970/4885NOS2 1669/4885 |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | OPRM1, POLM, AP1M1 | ACHE 3852/4885KMT2A 895/4885NOS2 3571/4885 |
| US-20050192418-A1 | Heterocyclic metallocenes and polymerization catalysts | GAK, INTS9, ZYX | ACHE 3852/4885KMT2A 632/4885NOS2 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.