Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593129 | 0.79 | ACHE (0.40) | ACHENOTUMMAPTHPGD | |
| SCHEMBL817816 | 0.69 | ACHE (0.44) | ACHEPNMT | |
| SCHEMBL2774624 | 0.68 | ALDH1A1 (0.46) | NOS3NOS2MAPTHPGD | |
| SCHEMBL817973 | 0.67 | ACHE (0.46) | ACHENOS3NOS2 | |
| SCHEMBL7606949 | 0.66 | SIRT1 (0.32) | NOS3NOS2NOTUM | |
| SCHEMBL2775298 | 0.65 | PNMT (0.37) | NOS3NOS2NOTUMHPGDPNMT | |
| SCHEMBL13963484 | 0.65 | PNMT (0.43) | NOS3NOS2NOTUMMAPTHPGD | |
| SCHEMBL1823806 | 0.65 | NOS3 (0.39) | NOS3NOS2MAPTPNMT | |
| SCHEMBL3658017 | 0.64 | ACHE (0.61) | ACHEMAPTHPGD | |
| SCHEMBL22608077 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11578148-B2 | Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-02-14 | — | — | US | disclosed |
| US-11578148-B2 | Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-02-14 | — | — | US | disclosed |
| EP-3732183-B1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands Bv (NL) | 2021-10-20 | — | — | EP | disclosed |
| EP-3732183-B1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands Bv (NL) | 2021-10-20 | — | — | EP | disclosed |
| US-20210087305-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2021-03-25 | — | — | US | disclosed |
| US-20210087305-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2021-03-25 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-08-09 | — | — | US | disclosed |
| WO-2007070046-A1 | HALOGEN SUBSTITUTED HETEROATOM-CONTAINING METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007070046-A1 | HALOGEN SUBSTITUTED HETEROATOM-CONTAINING METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070142649-A1 | Reacting a thiophene or 1-substituted pyrrole with a methacrylic acid or anhydride or derivated to form a fused thieno(c)cyclopentanone or pyrrolo(c)cyclopentanone in the presence of a strong acid (methane sulfonic acid) and a water absorbent (P2O5) | BASELL POLYOLEFINE GMBH (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070142649-A1 | Reacting a thiophene or 1-substituted pyrrole with a methacrylic acid or anhydride or derivated to form a fused thieno(c)cyclopentanone or pyrrolo(c)cyclopentanone in the presence of a strong acid (methane sulfonic acid) and a water absorbent (P2O5) | BASELL POLYOLEFINE GMBH (DE) | 2007-06-21 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| EP-1572677-B1 | PREPARATION OF HETEROCYCLIC KETONES | BASELL POLYOLEFINE GMBH (DE) | 2006-04-12 | — | — | EP | disclosed |
| EP-1572677-A1 | PREPARATION OF HETEROCYCLIC KETONES | Basell Polyolefine GmbH (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056796-A1 | PREPARATION OF HETEROCYCLIC KETONES | BASELL POLYOLEFINE GMBH (DE) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087305-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | AP3M1, AP2M1, AP1M1 | ACHE 2801/4885NOS3 3748/4885NOS2 4230/4885 |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | OPRM1, POLM, AP1M1 | ACHE 3852/4885NOS3 3566/4885NOS2 3571/4885 |
| US-11578148-B2 | Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands | AP3M1, AP2M1, AP1M1 | ACHE 2801/4885NOS3 3748/4885NOS2 4230/4885 |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | OPRM1, POLM, AP1M1 | ACHE 3852/4885NOS3 3566/4885NOS2 3571/4885 |
| US-20070142649-A1 | Reacting a thiophene or 1-substituted pyrrole with a methacrylic acid or anhydride or derivated to form a fused thieno(c)cyclopentanone or pyrrolo(c)cyclopentanone in the presence of a strong acid (methane sulfonic acid) and a water absorbent (P2O5) | PYCR1, CBR1, AKR1C3 | ACHE 4275/4885NOS3 484/4885NOS2 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.