Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595099 | 0.90 | HSD11B1 (0.49) | HSD11B1P2RX7HCAR1NR3C1PGR | |
| SCHEMBL10592781 | 0.86 | HSD11B1 (0.45) | HSD11B1P2RX7HCAR1RXFP1MAPT | |
| SCHEMBL10593971 | 0.81 | HSD11B1 (0.48) | HSD11B1HCAR1MAPTALDH1A1LMNA | |
| SCHEMBL10594058 | 0.81 | HSD11B1 (0.49) | HSD11B1P2RX7NR3C1PGRRXFP1 | |
| SCHEMBL10594895 | 0.80 | P2RX7 (0.42) | HSD11B1P2RX7HCAR1MAPTALDH1A1 | |
| SCHEMBL10601471 | 0.80 | HCAR1 (0.37) | HSD11B1P2RX7HCAR1NR1H2NR1H3 | |
| SCHEMBL10593715 | 0.80 | HSD11B1 (0.36) | HSD11B1P2RX7HCAR1NR3C1NR1H2 | |
| SCHEMBL10592226 | 0.80 | HSD11B1 (0.54) | HSD11B1P2RX7NR3C1NR1H2NR1H3 | |
| SCHEMBL10593160 | 0.79 | MAPT (0.41) | PGRMAPTARALDH1A1TRPA1 | |
| SCHEMBL10594791 | 0.78 | HCAR1 (0.39) | HSD11B1P2RX7HCAR1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871757-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0208321-A2 | Triazole derivatives, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1987-01-14 | — | — | EP | disclosed |