Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593347 | 0.83 | L3MBTL1 (0.43) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL9813210 | 0.70 | MAPT (0.41) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL16061814 | 0.69 | L3MBTL1 (0.43) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL10590538 | 0.69 | MEN1 (0.40) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL10591953 | 0.69 | EPHX2 (0.41) | GAAMAPTMEN1KMT2ANOX1 | |
| SCHEMBL2987616 | 0.68 | SNCA (0.50) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL1201818 | 0.68 | L3MBTL1 (0.45) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL9813116 | 0.67 | NOX1 (0.41) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL9813103 | 0.66 | GAA (0.39) | L3MBTL1GAAMAPTMEN1KMT2A | |
| SCHEMBL10591310 | 0.66 | NOX1 (0.40) | L3MBTL1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115394-B1 | PHENOTHIAZONE DERIVATIVES AND ANALOGS | MERCK FROSST CANADA INC. (CA) | 1989-06-28 | — | — | EP | disclosed |
| EP-0155623-A2 | Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition | MERCK & CO. INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0115394-A2 | Phenothiazone derivatives and analogs | MERCK FROSST CANADA INC. (CA) | 1984-08-08 | — | — | EP | disclosed |