SCHEMBL1201818

SCHEMBL1201818

CC1=CC2=C(CC1=O)Sc1ccccc1N2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ GAA P10253 9/20 0.43
▸ MAPT P10636 8/20 0.43
▸ MEN1 O00255 7/20 0.43
▸ KMT2A Q03164 7/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ NOX1 Q9Y5S8 8/20 0.43
▸ ALOX15 P16050 3/20 0.43
▸ TDP1 Q9NUW8 3/20 0.43
▸ SNCA P37840 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ BCHE P06276 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ ADORA3 P0DMS8 1/20 0.43
▸ ALOX12 P18054 1/20 0.43
▸ MAOA P21397 1/20 0.43
▸ CNR1 P21554 1/20 0.43
▸ ACHE P22303 1/20 0.43
▸ PTGS1 P23219 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10593297 0.84 EPHX2 (0.47) GAAMAPTMEN1KMT2ANOX1
SCHEMBL10590535 0.74 SOAT1 (0.40) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL87790 0.73 GAA (0.47) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL11818621 0.69 GAA (0.46) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL10593347 0.68 L3MBTL1 (0.43) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL10593192 0.68 L3MBTL1 (0.43) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL10352648 0.67 GAA (0.52) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL7790923 0.67 NOX1 (0.52) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL17363539 0.67 NOX1 (0.43) L3MBTL1GAAMAPTMEN1KMT2A
SCHEMBL9813228 0.66 SNCA (0.52) L3MBTL1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202987-B2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2007-04-10 — — US claimed
US-6954300-B2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such sold films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2005-10-11 — — US claimed
US-20050079326-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2005-04-14 — — US claimed
US-6154306-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-11-28 — — US claimed
EP-1004649-A2 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 2000-05-31 — — EP claimed
US-6002511-A Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices DONNELLY CORPORATION (US) 1999-12-14 — — US claimed
US-5500760-A Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1996-03-19 — — US claimed
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 — — EP claimed
EP-0531143-A2 Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1993-03-10 — — EP claimed
US-8610992-B2 Variable transmission window DONNELLY CORPORATION (US) 2013-12-17 — — US disclosed
US-8559093-B2 Electrochromic mirror reflective element for vehicular rearview mirror assembly DONNELLY CORPORATION (US) 2013-10-15 — — US disclosed
US-20130063802-A1 VARIABLE TRANSMISSION WINDOW DONNELLY CORPORATION (US) 2013-03-14 — — US disclosed
US-8294975-B2 Automotive rearview mirror assembly DONNELLY CORPORATION (US) 2012-10-23 — — US disclosed
US-20120206790-A1 ELECTROCHROMIC MIRROR REFLECTIVE ELEMENT FOR VEHICULAR REARVIEW MIRROR ASSEMBLY DONNELLY CORPORATION (US) 2012-08-16 — — US disclosed
US-5500760-A Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1996-03-19 — — US disclosed
EP-0612826-A1 Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processing for making such solid films and devices DONNELLY CORPORATION (US) 1994-08-31 — — EP disclosed
EP-0531143-A2 Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same DONNELLY CORPORATION (US) 1993-03-10 — — EP disclosed
EP-0115394-B1 PHENOTHIAZONE DERIVATIVES AND ANALOGS MERCK FROSST CANADA INC. (CA) 1989-06-28 — — EP disclosed
EP-0155623-A2 Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition MERCK & CO. INC. (US) 1985-09-25 — — EP disclosed
EP-0115394-A2 Phenothiazone derivatives and analogs MERCK FROSST CANADA INC. (CA) 1984-08-08 — — EP disclosed
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