SCHEMBL10593265

SCHEMBL10593265

O=[N+]([O-])C=C(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.47
TLR2 O60603 1/20 0.47
ALDH1A1 P00352 4/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
PRMT1 Q99873 1/20 0.47
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
FBP1 P09467 5/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
POLB P06746 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL27731617 0.92 ALDH1A1 (0.54) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL27814675 0.83 TLR4 (0.45) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL5067634 0.78 MAPT (0.49) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL1986025 0.78 TLR4 (0.66) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL5067640 0.78 MAPT (0.49) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL1986023 0.78 TLR4 (0.66) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL6475510 0.78 PRMT1 (0.63) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL6475515 0.78 PRMT1 (0.63) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL1986024 0.78 TLR4 (0.66) TLR4TLR2ALDH1A1MAPTLMNA
SCHEMBL8626889 0.78 MAPT (0.49) TLR4TLR2ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057268-A Stable aliphatic dinitrile oxide cross-linking agent, cross-linked body and preparation method thereof 西南科技大学 2020-04-24 CN claimed
CN-110157504-A The automobile-used boat alcohol fuel calorific value Synergistic additives of one kind and production method 寇延华 2019-08-23 CN claimed
CN-104004189-A Photosensitive polyimide preparation method, photosensitive polyimide orientation film making method, and display device BEIJING BOE OPTOELECTRONICS 2014-08-27 CN claimed
CN-103709767-A Mixing-type rubber powder modified emulsified asphalt and preparation method thereof XUCHANG GOLDROAD ASPHALT CO LTD 2014-04-09 CN claimed
CN-101880525-B Liquid phosphor composition and light emitting device IND TECH RES INST 2013-10-16 CN claimed
CN-103044344-A Benzotriazol derivatives containing o-nitro-diphenyl ethylene fragments UNIV CHONGQING 2013-04-17 CN claimed
CN-101880525-A Liquid phosphor composition and light emitting device IND TECH RES INST 2010-11-10 CN claimed
CN-101225241-B Non-conjugated p-nitro diphenyl ethylene dye containing benzophenone via ether linkage as well as synthesis and uses thereof UNIV CHONGQING 2010-05-26 CN claimed
CN-101367889-A Para nitro toluylene near ultraviolet photosencitizer, synthesis and uses thereof UNIV CHONGQING (CN) 2009-02-18 CN claimed
CN-101367890-A Para nitro toluylene visible light photosencitizer, synthesis and uses thereof UNIV CHONGQING (CN) 2009-02-18 CN claimed
CN-101225241-A Non-conjugated p-nitro diphenyl ethylene dye containing benzophenone via ether linkage as well as synthesis and uses thereof UNIV CHONGQING (CN) 2008-07-23 CN claimed
CN-1994087-A Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice AVENTIS CROPSCIENCE GMBH (DE) 2007-07-11 CN claimed
CN-1243722-C Preparation method of amino stilbene derivative AJINOMOTO KK (JP) 2006-03-01 CN claimed
CN-1518535-A Preparation method of amino stilbene derivative ֮����ʽ���� 2004-08-04 CN claimed
CN-1314785-A Herbicidal compositions containing substituted phenylsulfonylureas for controlling paddy-field weeds HOECHST SCHERING AGREVO GMBH (DE) 2001-09-26 CN claimed
CN-1169099-A Synergistic herbicidal agents based on glufosinates and nitrodiphenyl ethers and their formulations HOECHST SCHERING AGREVO GMBH (DE) 1997-12-31 CN claimed
JP-63132865-A None JP disclosed
US-12275749-B2 Rotaxane compound SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2025-04-15 US disclosed
US-4474989-A Process for preparing dinitrobenzophenones GULF RESEARCH & DEVELOPMENT COMPANY (US) 1984-10-02 US disclosed
EP-0098677-A2 Process for preparing dinitrobenzophenones CHEVRON RESEARCH COMPANY (US) 1984-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12275749-B2 Rotaxane compound CAPN9, CAPN1, CAPN2 TLR4 3282/4885TLR2 4369/4885ALDH1A1 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.