Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067640 | 1.00 | MAPT (0.49) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL5067634 | 1.00 | MAPT (0.49) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL4067060 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL4067059 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL1160340 | 0.82 | MAPT (0.45) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL3963190 | 0.80 | L3MBTL1 (0.44) | MAPTALDH1A1L3MBTL1LMNAMEN1 | |
| SCHEMBL8629293 | 0.80 | TSHR (0.67) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8629294 | 0.80 | TSHR (0.67) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8629297 | 0.80 | TSHR (0.67) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10593265 | 0.78 | TLR4 (0.47) | MAPTALDH1A1L3MBTL1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |