Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201818 | 0.84 | L3MBTL1 (0.45) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL10591877 | 0.79 | EPHX2 (0.48) | EPHX2MAPTMEN1KMT2AALOX15 | |
| SCHEMBL10590860 | 0.75 | EPHX2 (0.47) | EPHX2MAPTMEN1KMT2AALOX15 | |
| SCHEMBL9813228 | 0.71 | SNCA (0.52) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL10591899 | 0.71 | NOX1 (0.43) | MAPTMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL11287177 | 0.70 | KDM4E (0.31) | MAPTMEN1KMT2AGAANOX1 | |
| SCHEMBL10591953 | 0.70 | EPHX2 (0.41) | EPHX2MAPTMEN1KMT2AALOX15 | |
| SCHEMBL29640485 | 0.69 | MAPT (0.59) | EPHX2MAPTMEN1KMT2AALOX15 | |
| SCHEMBL225916 | 0.69 | MAPT (0.59) | EPHX2MAPTMEN1KMT2AALOX15 | |
| SCHEMBL10592010 | 0.69 | NOX1 (0.39) | MAPTMEN1KMT2AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115394-B1 | PHENOTHIAZONE DERIVATIVES AND ANALOGS | MERCK FROSST CANADA INC. (CA) | 1989-06-28 | — | — | EP | disclosed |
| EP-0155623-A2 | Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition | MERCK & CO. INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0115394-A2 | Phenothiazone derivatives and analogs | MERCK FROSST CANADA INC. (CA) | 1984-08-08 | — | — | EP | disclosed |