Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.48 |
| ▸ | HRH2 | P25021 | 11/20 | 0.48 |
| ▸ | HRH1 | P35367 | 11/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526681 | 1.00 | HRH3 (0.48) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL10399387 | 0.91 | HRH3 (0.48) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL10594224 | 0.91 | HRH3 (0.48) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL10399304 | 0.84 | ALDH1A1 (0.52) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL16437754 | 0.84 | MMP2 (0.51) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL16437757 | 0.84 | MMP2 (0.51) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL21227055 | 0.84 | TDP1 (0.47) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL5624212 | 0.83 | MMP2 (0.60) | HRH3HRH2HRH1MMP2MMP3 | |
| SCHEMBL16437760 | 0.82 | HRH3 (0.50) | HRH3HRH2HRH1MMP2ALDH1A1 | |
| SCHEMBL10399310 | 0.82 | ALDH1A1 (0.56) | HRH3HRH2HRH1MMP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4844836-A | LIQUID CRYSTALS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | claimed |
| US-4844836-A | LIQUID CRYSTALS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |