Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504192 | 0.90 | ADRB2 (0.37) | ADRB2ADRB1ADRB3MEN1CYP1A2 | |
| SCHEMBL10503910 | 0.84 | ADRB1 (0.40) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10504729 | 0.78 | ADRB1 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10505162 | 0.78 | ADRB1 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10503927 | 0.78 | ADRB3 (0.51) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10504024 | 0.77 | ADRB2 (0.41) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10504922 | 0.76 | ADRB1 (0.46) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10504355 | 0.75 | ADRB2 (0.37) | ADRB2ADRB1ADRB3MEN1CYP1A2 | |
| SCHEMBL10504002 | 0.75 | ADRB3 (0.56) | ADRB2ADRB1ADRB3KDM4EKMT2A | |
| Fumaric Acid SCHEMBL10504541 | 0.75 | ADRB1 (0.51) | ADRB2ADRB1ADRB3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |