Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10593255 | 0.98 | L3MBTL1 (0.40) | L3MBTL1ADRB2ADRB1CYP1A2ADRB3 | |
| SCHEMBL10504268 | 0.89 | ADRB2 (0.44) | ADRB2ADRB1CYP1A2ADRB3MEN1 | |
| SCHEMBL10504578 | 0.89 | L3MBTL1 (0.41) | L3MBTL1ADRB2ADRB1CYP1A2ADRB3 | |
| SCHEMBL10594457 | 0.87 | ADRB2 (0.36) | L3MBTL1ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL10591715 | 0.86 | CYP2D6 (0.38) | L3MBTL1ADRB2CYP1A2MEN1KMT2A | |
| SCHEMBL10594583 | 0.84 | CYP2D6 (0.37) | L3MBTL1ADRB2CYP1A2MEN1KMT2A | |
| SCHEMBL10503760 | 0.81 | L3MBTL1 (0.48) | L3MBTL1ADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL10504801 | 0.81 | SLC6A2 (0.51) | ADRB2ADRB1CYP1A2ADRB3MEN1 | |
| SCHEMBL10594588 | 0.79 | CYP2D6 (0.45) | ADRB2ADRB1CYP1A2ADRB3MEN1 | |
| SCHEMBL10503152 | 0.79 | L3MBTL1 (0.48) | L3MBTL1ADRB2ADRB1ADRB3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863949-A | CARDIOVASCULAR DISORDER TREATMENT | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |