SCHEMBL10594591

SCHEMBL10594591

CC1(C)CCC(CBr)(c2ccc(Cl)cc2)O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
SLC6A4 P31645 6/20 0.36
SLC6A3 Q01959 6/20 0.36
UTS2R Q9UKP6 7/20 0.35
SLC6A2 P23975 3/20 0.35
EGFR P00533 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
KDM1A O60341 1/20 0.33
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11044632 0.74 UTS2R (0.40) SLC6A4SLC6A3UTS2RSLC6A2EGFR
SCHEMBL10595423 0.72 CYP3A4 (0.43) ALDH1A1SLC6A4SLC6A3SLC6A2CYP3A4
SCHEMBL10594327 0.68 SLC6A3 (0.33) SLC6A4SLC6A3UTS2RSLC6A2MAOA
SCHEMBL28869919 0.67 EGFR (0.74) UTS2REGFR
SCHEMBL10593453 0.67 SLC6A4 (0.36) ALDH1A1SLC6A4SLC6A3SLC6A2MAOA
SCHEMBL1041125 0.66 SLC6A4 (0.52) ALDH1A1SLC6A4SLC6A3SLC6A2MAOA
SCHEMBL28309660 0.66 UTS2R (0.43) SLC6A4SLC6A3UTS2REGFRMAOA
SCHEMBL28618351 0.64 SLC6A4 (0.39) ALDH1A1SLC6A4SLC6A3UTS2RSLC6A2
SCHEMBL3121940 0.63 SLC6A4 (0.58) ALDH1A1SLC6A4SLC6A3SLC6A2MAOA
SCHEMBL10876682 0.63 SLC6A4 (0.40) SLC6A4SLC6A3UTS2RSLC6A2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089100-B1 AZOLYL DERIVATIVES AS FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-31 EP disclosed
US-4518415-A PLANT GROWTH REGULATORS, FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-21 US disclosed
EP-0089100-A2 Azolyl derivatives as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-09-21 EP disclosed