Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.37 |
| ▸ | CHRNG | P07510 | 2/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRND | Q07001 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10638461 | 0.81 | UTS2R (0.38) | UTS2RMAOAMAOBKDM1ASLC6A4 | |
| SCHEMBL9667369 | 0.79 | SLC6A4 (0.41) | UTS2RMAOAMAOBKDM1ASLC6A4 | |
| SCHEMBL10876682 | 0.79 | SLC6A4 (0.40) | UTS2RKDM1ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7787371 | 0.77 | HTR2C (0.43) | SLC6A4SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL10434640 | 0.76 | UTS2R (0.35) | UTS2RMAOAMAOBKDM1ASLC6A4 | |
| SCHEMBL8807095 | 0.76 | UTS2R (0.38) | UTS2RMAOAMAOBSLC6A4SLC6A3 | |
| SCHEMBL866796 | 0.75 | SLC6A3 (0.37) | UTS2RMAOAMAOBKDM1ASLC6A4 | |
| SCHEMBL10594591 | 0.74 | ALDH1A1 (0.37) | UTS2RMAOAMAOBKDM1ASLC6A4 | |
| SCHEMBL117206 | 0.73 | MAOA (0.38) | UTS2RMAOAMAOBKDM1ASLC6A4 | |
| SCHEMBL11273687 | 0.73 | UTS2R (0.40) | UTS2RSLC6A4SLC6A3SLC6A2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122452-A1 | Triazolyl- and imidazolyl-substituted fluoroalkane derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-10-24 | — | — | EP | disclosed |