SCHEMBL10593453

SCHEMBL10593453

C=CC1(c2ccc(Cl)cc2)CCC(C)(C)O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.36
SLC6A3 Q01959 9/20 0.36
KMT2A Q03164 2/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TET3 O43151 1/20 0.33
FBXL19 Q6PCT2 1/20 0.33
CXXC5 Q7LFL8 1/20 0.33
KDM2B Q8NHM5 1/20 0.33
CXXC4 Q9H2H0 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
SLC6A2 P23975 4/20 0.32
CHRNA1 P02708 2/20 0.32
CHRNG P07510 2/20 0.32
CHRNB1 P11230 2/20 0.32
CHRNB2 P17787 2/20 0.32
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNA4 P43681 2/20 0.32
CHRND Q07001 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10594591 0.67 ALDH1A1 (0.37) SLC6A4SLC6A3ALDH1A1SLC6A2CHRNA1
SCHEMBL435094 0.63 SLC6A4 (0.44) SLC6A4SLC6A3KMT2AMAPK1SLC6A2
SCHEMBL436499 0.60 SLC6A4 (0.46) SLC6A4SLC6A3MAPK1ALDH1A1SLC6A2
SCHEMBL27783629 0.60 SLC6A4 (0.47) SLC6A4SLC6A3KMT2AMAPK1ALDH1A1
SCHEMBL990597 0.60 SLC6A4 (0.47) SLC6A4SLC6A3KMT2AMAPK1ALDH1A1
SCHEMBL2737147 0.60 SLC6A3 (0.50) SLC6A4SLC6A3SLC6A2DRD2CCR2
Hydrochloric Acid SCHEMBL29020111 0.60 OPRM1 (0.42) SLC6A4SLC6A3KMT2AMAPK1SLC6A2
SCHEMBL16553770 0.60 DRD2 (0.55) SLC6A4SLC6A3KMT2ATET3FBXL19
SCHEMBL17807530 0.60 ALDH1A1 (0.41) SLC6A4SLC6A3ALDH1A1SLC6A2CHRNA1
SCHEMBL16484876 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0089100-B1 AZOLYL DERIVATIVES AS FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-05-31 EP disclosed
US-4518415-A PLANT GROWTH REGULATORS, FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-21 US disclosed
EP-0089100-A2 Azolyl derivatives as fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-09-21 EP disclosed