Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 17/20 | 0.48 |
| ▸ | CA1 | P00915 | 16/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11899474 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1CA2CA1CA4 | |
| Lithium Ion SCHEMBL4344880 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1CA2CA1CA4 | |
| Zinc Ion SCHEMBL31675793 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1CA2CA1CA4 | |
| Potassium Ion SCHEMBL3839472 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1CA2CA1CA4 | |
| SCHEMBL1886823 | 0.95 | CA2 (0.54) | ALDH1A1TDP1CA2CA1CA4 | |
| SCHEMBL9742682 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1CA2CA1CA4 | |
| Water SCHEMBL2997724 | 0.93 | ALDH1A1 (0.48) | ALDH1A1TDP1CA2CA1CA4 | |
| SCHEMBL10896479 | 0.83 | CA2 (0.42) | ALDH1A1TDP1CA2CA1CA4 | |
| SCHEMBL10894965 | 0.82 | CA2 (0.47) | ALDH1A1TDP1CA2CA1CA4 | |
| Silver SCHEMBL11600672 | 0.81 | CA2 (0.52) | ALDH1A1CA2CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614046-B2 | Salt and photoresist composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-24 | — | — | US | disclosed |
| US-20110014566-A1 | SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014566-A1 | SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME | XPA, NPPA, ERCC4 | ALDH1A1 3326/4885TDP1 1902/4885CA2 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.