Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6927452 | 0.84 | CDC25B (0.55) | CNR2ALDH1A1PLK1HDAC8MMP3 | |
| SCHEMBL3792160 | 0.81 | PLK1 (0.58) | CNR2CNR1ALDH1A1PLK1HDAC8 | |
| SCHEMBL31060081 | 0.81 | PLK1 (0.58) | CNR2CNR1ALDH1A1PLK1HDAC8 | |
| SCHEMBL2117237 | 0.80 | TSHR (0.73) | CNR2CNR1CYP2C9TSHRTP53 | |
| SCHEMBL14058606 | 0.80 | TSHR (0.66) | CNR2CNR1TSHRPLK1HDAC8 | |
| SCHEMBL4407176 | 0.79 | ALDH1A1 (0.74) | CNR2CNR1CYP2C9TSHRTP53 | |
| SCHEMBL1286894 | 0.79 | NAAA (0.67) | CNR2CNR1TSHRMAPK1PLK1 | |
| SCHEMBL9288049 | 0.79 | ALDH1A1 (0.74) | CNR2CNR1CYP2C9TSHRTP53 | |
| SCHEMBL20100237 | 0.79 | ALDH1A1 (0.74) | CNR2CNR1CYP2C9TSHRTP53 | |
| SCHEMBL30295637 | 0.79 | ALDH1A1 (0.74) | CNR2CNR1CYP2C9TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322256-A1 | N-acyl-N-naphthoylglycines as aldose reductase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-06-28 | — | — | EP | disclosed |