Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499912 | 0.91 | POLB (0.34) | POLBALDH1A1APEX1MEN1KMT2A | |
| SCHEMBL5697079 | 0.75 | CA1 (0.31) | — | |
| SCHEMBL3417324 | 0.72 | GAA (0.37) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL9525879 | 0.72 | NPC1 (0.33) | ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL19183362 | 0.70 | — | — | |
| SCHEMBL176317 | 0.69 | CA1 (0.35) | POLBTDP1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9512174 | 0.67 | ALDH1A1 (0.31) | ALDH1A1GAAHPGD | |
| SCHEMBL9815332 | 0.67 | KDM4E (0.42) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL982574 | 0.67 | L3MBTL1 (0.58) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8106146 | 0.67 | KDM4E (0.35) | POLBALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207396-B1 | TETRAHYDROFURANCARBOXYLIC-ACID DERIVATIVES | BASF Aktiengesellschaft (DE) | 1989-04-19 | — | — | EP | disclosed |
| EP-0207396-A1 | Tetrahydrofurancarboxylic-acid derivatives | BASF Aktiengesellschaft (DE) | 1987-01-07 | — | — | EP | disclosed |