Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499630 | 0.80 | HSD17B10 (0.37) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10596179 | 0.72 | POLB (0.40) | SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL1800550 | 0.71 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8106146 | 0.67 | KDM4E (0.35) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL183194 | 0.67 | RAB9A (0.42) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL6966557 | 0.67 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL982574 | 0.67 | L3MBTL1 (0.58) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9815332 | 0.67 | KDM4E (0.42) | SMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6397225 | 0.67 | KDM4E (0.42) | SMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL10846303 | 0.67 | ALDH1A1 (0.48) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349862-B1 | 2,6 polyalkyl piperidine-4-amides, their use as stabilizers in particular for synthetic materials as well as the organic material containing them | BASF AG (DE) | 1993-10-27 | — | — | EP | disclosed |
| EP-0349862-A1 | 2,6 polyalkyl piperidine-4-amides, their use as stabilizers in particular for synthetic materials as well as the organic material containing them | BASF Aktiengesellschaft (DE) | 1990-01-10 | — | — | EP | disclosed |