Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319789 | 0.90 | THRB (0.40) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9320461 | 0.90 | THRB (0.40) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9319769 | 0.90 | THRB (0.40) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9322186 | 0.81 | THRB (0.41) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9320177 | 0.79 | THRB (0.36) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9320244 | 0.79 | THRB (0.36) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9320168 | 0.79 | THRB (0.36) | THRBTHRAMCHR1SERPINE1 | |
| SCHEMBL9769332 | 0.73 | MMP1 (0.39) | MMP13 | |
| SCHEMBL9768653 | 0.73 | CA2 (0.41) | THRBTHRACA1CA2CA9 | |
| SCHEMBL6151750 | 0.69 | THRB (0.39) | THRBTHRAMCHR1PNMTSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840887-A | USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |